Summary of “Improved Peyronie’s Disease Curvature Outcomes Using a Novel Collagenase Administration Protocol” Collagenase Clostridium Histolyticum (CCH) can be used on men with Peyronie’s Disease (PD) to improve penile curvature. Since the release of CCH in 2014 studies have consistently shown penile curvature improvements in men with PD in the 14-23˚ range (similar to findings […]
The following is a summary of an article recently published in the Journal of Sexual Medicine. We provide these summaries in the hopes that they will help patients keep up to date on the latest research published on the topics of PD and male infertility. This particular study’s goal was to define the factors that
What is Peyronie’s disease? Peyronie’s disease (PD) is a connective tissue disorder affecting the tunica albuginea and is characterized by penile curvature resulting from fibrosis and plaque deposits. PD can not only cause physical pain, but it can also cause psychological and psychosexual issues. PD affects between 0.4 to 20+% of the male population (depending
What Causes Peyronie’s Disease? Read More »
Peyronie’s Disease (PD) is a fibrotic disorder of the tunica albuginea of the corpora cavernosa and is progressive in nature. Consequently, this disorder is linked to a decrease in sexual performance and self-confidence. Currently, treatments include oral medication, surgical reconstruction, and injectable therapy. The purpose of this study was to compare the costs of treatment
Peyronie’s Disease (PD) is a connective tissue disorder of the penis affecting the tunica albuginea. This disorder can lead to penile deformity and local pain. No one knows what causes PD; however, it is thought that PD could be caused by repetitive microvascular trauma, causing inflammation, excessive collagen deposition, and fibrinogenesis on the tunica albuginea.
Peyronie’s Disease can be a diagnosis that can be troubling for men to even accept or speak to their physician about but it is important to know the causes of this condition.
Causes and diagnosis of Peyronie’s Disease Read More »
***Trost Commentary and Key Take-Home Points*** The current study specifically investigates Peyronie’s Disease in teenagers and compares their condition to that of men >40 years old. The diagnosis of PD is often confused with congenital penile curvature (CPC) in younger men. CPC is typically a life-long curvature and is not typically associated with penile plaques. It also
Summary of “Peyronie’s Disease in Teenagers” Read More »
***Trost Commentary and Key Take-Home Points*** The current manuscript examines a modification to a technique that is performed at the time of penile prosthesis placement to achieve greater penile length. Basically, several years back, a technique was developed known as the ‘sliding’ technique, where the penis was basically nearly amputated, stretched, and placed over a
***Trost Commentary and Key Take-Home Points*** The current review article discusses some of the complexities of the process by which Peyronie’s Disease leads to penile fibrosis and scarring. The key take home point is that, to date, there are no good treatments which have been shown to prevent the progression of Peyronie’s Disease scarring. Although
***Trost Commentary and Key Take-Home Points*** This summary is of an abstract that was presented at the SMSNA meeting (SMSNA.org) but has not yet been published. This abstract is excellent though, and it highlights some very important aspects of PD. Specifically, many (? most) men with PD are concerned about how the condition may affect