Injectables

Summary of “Intralesional Injection of Hyaluronic Acid in Patients Affected With Peyronie’s Disease: Preliminary Results From a Prospective, Multicenter, Pilot Study”

***Trost Commentary and Key Take-Home Points*** The current study evaluates the use of intralesional hyaluronic acid to treat Peyronie’s Disease.  This is one of 4 different types of injections which are most commonly reported, with the others being collagenase (Xiaflex), interferon, and verapamil.  This specific injection is more commonly used in Europe, particularly now that collagenase is no …

Summary of “Intralesional Injection of Hyaluronic Acid in Patients Affected With Peyronie’s Disease: Preliminary Results From a Prospective, Multicenter, Pilot Study” Read More »

Summary of “Characteristics of Men With Peyronie’s Disease and Collagenase Clostridium Histolyticum Treatment Failure: Predictors of Surgical Intervention and Outcomes”

***Trost Commentary and Key Take-Home Points*** This manuscript represents a nice review of outcomes of patients who undergo surgery post Xiaflex treatment.  The key finding from the study is that surgery remains a viable option for men who do not experience a sufficient improvement with Xiaflex.  I think it’s important to recognize that the key finding from the study should …

Summary of “Characteristics of Men With Peyronie’s Disease and Collagenase Clostridium Histolyticum Treatment Failure: Predictors of Surgical Intervention and Outcomes” Read More »

Summary of, “Comparison of Intralesional Hyaluronic Acid vs. Verapamil for the Treatment of Acute Phase Peyronie’s Disease: A Prospective, Open-Label Non-Randomized Clinical Study.”

—Dr. Trost Commentary and Key Take Home Points— This current study evaluates the use of two different injection treatments for men with early phase Peyronie’s Disease.  This study was performed by an experienced group of researchers in Italy.  This is important to recognize though, as the gold-standard injection treatment (Xiaflex) is more difficult to use …

Summary of, “Comparison of Intralesional Hyaluronic Acid vs. Verapamil for the Treatment of Acute Phase Peyronie’s Disease: A Prospective, Open-Label Non-Randomized Clinical Study.” Read More »

Summary of "How Atypical Penile Curvature Influence Clinical Outcomes in Patients with Peyronie’s Disease Receiving Collagenase Clostridium Histolyticum Therapy?"

—Dr. Trost Commentary and Key Take-home Points—  The current manuscript evaluates the efficacy of Xiaflex in improving curvature in men with less common deformities, including those with downward curvatures, hourglass deformity, or decreased penile length.  Not surprisingly, results showed that the therapy is indeed able to improve curvature in these conditions as well.  In our own experience, we …

Summary of "How Atypical Penile Curvature Influence Clinical Outcomes in Patients with Peyronie’s Disease Receiving Collagenase Clostridium Histolyticum Therapy?" Read More »

Scroll to Top