Summary of “Improved Peyronie’s Disease Curvature Outcomes Using a Novel Collagenase Administration Protocol” Collagenase Clostridium Histolyticum (CCH) can be used on men with Peyronie’s Disease (PD) to improve penile curvature. Since the release of CCH in 2014 studies have consistently shown penile curvature improvements in men with PD in the 14-23˚ range (similar to findings […]
The following is a summary of an article recently published in the Journal of Sexual Medicine. We provide these summaries in the hopes that they will help patients keep up to date on the latest research published on the topics of PD and male infertility. This particular study’s goal was to define the factors that
A commonly asked question we get at the Male Fertility and Peyronie’s Clinic is whether the use of surgical drains in the scrotum during a vasectomy reversal will improve the outcome of the surgery. This article will review what drains are and whether they impact outcomes of vasectomy reversals. What is a Surgical Drain? A
Summary of “Lifestyle causes of male infertility” Over the past few decades, there has arguably been a global decline in both sperm quality and quantity, although the true extent of changes remains an issue of ongoing debate among experts. The purpose of this article was to review available evidence regarding effects of men’s lifestyle factors
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What is Peyronie’s disease? Peyronie’s disease (PD) is a connective tissue disorder affecting the tunica albuginea and is characterized by penile curvature resulting from fibrosis and plaque deposits. PD can not only cause physical pain, but it can also cause psychological and psychosexual issues. PD affects between 0.4 to 20+% of the male population (depending
What Causes Peyronie’s Disease? Read More »
Peyronie’s Disease (PD) is a fibrotic disorder of the tunica albuginea of the corpora cavernosa and is progressive in nature. Consequently, this disorder is linked to a decrease in sexual performance and self-confidence. Currently, treatments include oral medication, surgical reconstruction, and injectable therapy. The purpose of this study was to compare the costs of treatment
What is COVID-19? Coronavirus (COVID-19 or SARS-CoV-2) is a highly contagious virus affecting the respiratory system and can be quite deadly. Since its origin, it has infected hundreds of millions of people around the world. While the primary mode of transmission is through respiratory droplets, COVID-19 has been found in feces, urine, and semen. With
Does COVID-19 Have an Impact on Male Fertility? Read More »
Peyronie’s Disease (PD) is a connective tissue disorder of the penis affecting the tunica albuginea. This disorder can lead to penile deformity and local pain. No one knows what causes PD; however, it is thought that PD could be caused by repetitive microvascular trauma, causing inflammation, excessive collagen deposition, and fibrinogenesis on the tunica albuginea.
***Trost Commentary and Key Take-Home Points*** This is one of the most helpful and impactful manuscripts currently available relating to vasectomy reversals in my opinion. It is also one of the manuscripts that we refer to most often for patients post-operatively. The main reason for this importance is because it helps to define numbers which are predictive of
Summary of “Vasectomy Reversal Semen Analysis: New Reference Ranges Predict Pregnancy” Read More »
***Trost Commentary and Key Take-Home Points*** The current manuscript compares penile length and infertility and suggests an association between the two. This type of study has been performed on several prior occasions as well, although a much more commonly used measure is the anogenital distance (AGD – distance between the anus and the genitals themselves) rather