Summary of “Improved Peyronie’s Disease Curvature Outcomes Using a Novel Collagenase Administration Protocol” Collagenase Clostridium Histolyticum (CCH) can be used on men with Peyronie’s Disease (PD) to improve penile curvature. Since the release of CCH in 2014 studies have consistently shown penile curvature improvements in men with PD in the 14-23˚ range (similar to findings […]
The following is a summary of an article recently published in the Journal of Sexual Medicine. We provide these summaries in the hopes that they will help patients keep up to date on the latest research published on the topics of PD and male infertility. This particular study’s goal was to define the factors that
What is Peyronie’s disease? Peyronie’s disease (PD) is a connective tissue disorder affecting the tunica albuginea and is characterized by penile curvature resulting from fibrosis and plaque deposits. PD can not only cause physical pain, but it can also cause psychological and psychosexual issues. PD affects between 0.4 to 20+% of the male population (depending
What Causes Peyronie’s Disease? Read More »
Peyronie’s Disease (PD) is a connective tissue disorder of the penis affecting the tunica albuginea. This disorder can lead to penile deformity and local pain. No one knows what causes PD; however, it is thought that PD could be caused by repetitive microvascular trauma, causing inflammation, excessive collagen deposition, and fibrinogenesis on the tunica albuginea.
The annual meeting of the Sexual Medicine Society of North America concluded on 10/27/2019. This is the largest and most respected sexual medicine society in North America and includes the greatest authorities on sexual medicine. There were several abstract that were presented at the meeting that relate to Peyronie’s Disease, and our objective with this
Summary of Key Studies from the Sexual Medicine Society Annual Meeting Read More »
—Dr. Trost Commentary and Key Take-home Points— The current manuscript evaluates the efficacy of Xiaflex in improving curvature in men with less common deformities, including those with downward curvatures, hourglass deformity, or decreased penile length. Not surprisingly, results showed that the therapy is indeed able to improve curvature in these conditions as well. In our own experience, we
—Dr. Trost’s Commentary and Key Take-home Points— The current study provides some additional valuable information on conditions associated with Peyronie’s Disease. Specifically, the authors found that diabetes is clearly correlated with the condition, but other diagnoses, including hypertension, obesity, high cholesterol, smoking, or metabolic syndrome are not clearly associated. Although this information is not new,