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Summary of “What about the partner? —factors associated with patient-perceived partner dyspareunia in men with Peyronie’s disease”

***Trost Commentary and Key Take-Home Points*** This was a study that we did of men who we treated for PD while at Mayo Clinic.  We basically asked all men to complete a questionnaire that included a question as to whether or not the condition caused their partner pain.  We then compared differences between men who answered yes or […]

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Summary of “Peyronie’s Disease Intervention Studies: An Exploration of Modern-Era Challenges in Study Design and Evaluating Treatment Outcomes”

***Trost Commentary and Key Take-Home Points*** This was a summary that Matt, Larry, Giorgio and I worked on to help other physicians better understand the Peyronie’s scientific literature. There are many challenges that come with trying to interpret Peyronie’s studies, and because of this, it is often important to critically evaluate any paper that is

Summary of “Peyronie’s Disease Intervention Studies: An Exploration of Modern-Era Challenges in Study Design and Evaluating Treatment Outcomes” Read More »

Summary of “Characteristics of Men With Peyronie’s Disease and Collagenase Clostridium Histolyticum Treatment Failure: Predictors of Surgical Intervention and Outcomes”

***Trost Commentary and Key Take-Home Points*** This manuscript represents a nice review of outcomes of patients who undergo surgery post Xiaflex treatment.  The key finding from the study is that surgery remains a viable option for men who do not experience a sufficient improvement with Xiaflex.  I think it’s important to recognize that the key finding from the study should

Summary of “Characteristics of Men With Peyronie’s Disease and Collagenase Clostridium Histolyticum Treatment Failure: Predictors of Surgical Intervention and Outcomes” Read More »

Summary of “Contemporary Thoughts on the Role of Shockwave Therapy in Peyronie’s Disease”

–Trost Commentary and Key Take-Aways– Shock wave therapy has recently become in vogue as an alternative treatment option for PD.  However, patients need to recognize that there really are no consistent data demonstrating any benefits.  The American Urological Association and the Sexual Medicine Society of North America both have position statements that indicate that shock

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Summary of, “Beyond Curvature: Prevalence and Characteristics of Penile Volume-Loss Deformities in Men With Peyronie’s Disease”

–Trost Commentary and Key Take-home Points– This current study highlights how common issues such as indentations, hourglass deformities, or other similar findings are among men with Peyronie’s Disease.  These types of deformities can be particularly bothersome for individuals as they may cause buckling, instability, or anxiety for men during penetrative intercourse (i.e. fear of instability

Summary of, “Beyond Curvature: Prevalence and Characteristics of Penile Volume-Loss Deformities in Men With Peyronie’s Disease” Read More »

Summary of, “Comparison of Intralesional Hyaluronic Acid vs. Verapamil for the Treatment of Acute Phase Peyronie’s Disease: A Prospective, Open-Label Non-Randomized Clinical Study.”

—Dr. Trost Commentary and Key Take Home Points— This current study evaluates the use of two different injection treatments for men with early phase Peyronie’s Disease.  This study was performed by an experienced group of researchers in Italy.  This is important to recognize though, as the gold-standard injection treatment (Xiaflex) is more difficult to use

Summary of, “Comparison of Intralesional Hyaluronic Acid vs. Verapamil for the Treatment of Acute Phase Peyronie’s Disease: A Prospective, Open-Label Non-Randomized Clinical Study.” Read More »

Summary of Key Studies from the Sexual Medicine Society Annual Meeting

The annual meeting of the Sexual Medicine Society of North America concluded on 10/27/2019.  This is the largest and most respected sexual medicine society in North America and includes the greatest authorities on sexual medicine.  There were several abstract that were presented at the meeting that relate to Peyronie’s Disease, and our objective with this

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Summary of "Evaluation of Oral Pentoxifylline, Colchicine, and Penile Traction for the Management of Peyronie’s Disease"

—Dr. Trost Commentary and Key Take Home Points —  The current study evaluates the combination of traction therapy and oral treatments for Peyronie’s Disease (pentoxifylline and colchicine).  Dr. Carrier is a well-known Andrologist with significant experience in Peyronie’s Disease (and is a great person as well).  This particular study adds value to the concept of using combination therapies for managing Peyronie’s Disease.  There are a few key

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Summary of "Verteporfin as a Medical Treatment in Peyronie’s Disease"

—Dr. Trost Commentary and Key Take-home Points— This is a great proof of concept study and goes directly after one of the mechanisms that is thought to contribute to Peyronie’s Disease.  The challenge with a therapy such as this, though, is that often, men are not even aware of the condition until the fibrotic tissue has already

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Summary of "Shaeer’s Anti-Scarring Technique: A Preventive Measure Against Corporal Fibrosis Upon Explantation of Infected Penile Implants"

—Dr. Trost Commentary and Key Take-home Points—  Although relatively uncommon, penile implant infections represent a challenging and potentially devastating complication of penile prosthesis surgery.  Revision surgery after prior infections can increase the level of difficulty and risk of intra- and post-operative complications.  In the current study, the authors proposed a possible mechanism to reduce the

Summary of "Shaeer’s Anti-Scarring Technique: A Preventive Measure Against Corporal Fibrosis Upon Explantation of Infected Penile Implants" Read More »

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