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Summary of “Modern treatment strategies for penile prosthetics in Peyronie’s disease: a contemporary clinical review”

***Trost Commentary and Key Take-Home Points*** The current manuscript is a review article (summarizes research publications performed by other teams) which discusses the role of penile prosthetics in men with Peyronie’s Disease.  Penile prosthetics have a clear role for the treatment of PD men who have erectile dysfunction which does not respond to PDE5 inhibitors (i.e. Viagra, Levitra,

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Summary of “What role do pharmaceuticals play in the treatment of Peyronie’s disease and is there a need for new emerging drugs?”

***Trost Commentary and Key Take-Home Points*** This is a great commentary which highlights the significant need that we have for better medications to treat Peyronie’s Disease.  For decades, dozens of medicines, herbals, topicals, and energy types of treatments have been used to try to treat Peyronie’s Disease.  And, with few exceptions, none of them have showed any true promise in

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Summary of “Intralesional Injection of Hyaluronic Acid in Patients Affected With Peyronie’s Disease: Preliminary Results From a Prospective, Multicenter, Pilot Study”

***Trost Commentary and Key Take-Home Points*** The current study evaluates the use of intralesional hyaluronic acid to treat Peyronie’s Disease.  This is one of 4 different types of injections which are most commonly reported, with the others being collagenase (Xiaflex), interferon, and verapamil.  This specific injection is more commonly used in Europe, particularly now that collagenase is no

Summary of “Intralesional Injection of Hyaluronic Acid in Patients Affected With Peyronie’s Disease: Preliminary Results From a Prospective, Multicenter, Pilot Study” Read More »

Summary of “OUTCOMES OF A NOVEL PENILE TRACTION DEVICE (RESTOREX) IN MEN WITH PEYRONIE’S DISEASE: A RANDOMIZED, SINGLE-BLINDED, CONTROLLED TRIAL”

***Trost Commentary and Key Take-Home Points*** This study was one that we conducted soon after RestoreX became available.  Our goal was to determine if the device resulted in any benefits or not in treating Peyronie’s Disease.  My experience with traction devices to that point had not been very good.  Specifically, we had previously performed a study where we evaluated whether

Summary of “OUTCOMES OF A NOVEL PENILE TRACTION DEVICE (RESTOREX) IN MEN WITH PEYRONIE’S DISEASE: A RANDOMIZED, SINGLE-BLINDED, CONTROLLED TRIAL” Read More »

Summary of “Peyronie’s Disease in Teenagers”

***Trost Commentary and Key Take-Home Points*** The current study specifically investigates Peyronie’s Disease in teenagers and compares their condition to that of men >40 years old.  The diagnosis of PD is often confused with congenital penile curvature (CPC) in younger men.  CPC is typically a life-long curvature and is not typically associated with penile plaques.  It also

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Summary of “Penile Size Restoration With Nondegloving Approach for Peyronie’s Disease: Initial Experience”

***Trost Commentary and Key Take-Home Points*** The current manuscript examines a modification to a technique that is performed at the time of penile prosthesis placement to achieve greater penile length.  Basically, several years back, a technique was developed known as the ‘sliding’ technique, where the penis was basically nearly amputated, stretched, and placed over a

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Summary of “Pathophysiology and Future Therapeutic Perspectives for Resolving Fibrosis in Peyronie’s Disease”

***Trost Commentary and Key Take-Home Points*** The current review article discusses some of the complexities of the process by which Peyronie’s Disease leads to penile fibrosis and scarring. The key take home point is that, to date, there are no good treatments which have been shown to prevent the progression of Peyronie’s Disease scarring. Although

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Summary of “Peyronie’s Disease and the Female Sexual Partner: A Comparison of the Male and Female Experience”

***Trost Commentary and Key Take-Home Points*** This summary is of an abstract that was presented at the SMSNA meeting (SMSNA.org) but has not yet been published.  This abstract is excellent though, and it highlights some very important aspects of PD.  Specifically, many (? most) men with PD are concerned about how the condition may affect

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Summary of “Shockwave Therapy in the Treatment of Peyronie’s Disease”

***Trost Commentary and Key Take-Home Points*** Shockwave therapy is a very hot topic in sexual medicine and is very commonly advertised for Peyronie’s Disease and erectile dysfunction.  However, as of August, 2020, shockwave therapy is not ready for primetime and should not be recommended or used in Peyronie’s Disease.  Although a full description of data behind that comment is

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